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Mania After Brain Injury:Neuroradiological and Metabolic Findings
Ann Neurol 27:652-659, Starkstein,S.E.,et al, 1990
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Article Abstract
We present a consecutive series of 8 patients who developed a manic episode after a brain injury.Five patients had cortical lesions(4 with damage to the right basotemporal region,and 1 with bilateral damage to the orbitofrontal area).While the other 3 patients had subcortical lesions (white matter of the right frontal lobe,right anterior limb of the internal capsule,and right head of the caudate),a fluorodeoxyglucose positron emission tomography scan showed hypometabolism in the right lateral basotemporal region in all 3 patients.These findings suggest a major role for the basal region of the right temporal lobe in the modulation of mood.
 
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behavioral disorder
cerebrovascular accident
cerebrovascular accident,posttraumatic
head injury
head injury,behavioral disorder with
mania
MRI
MRI,abnormal

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